Bhavya Gandhi as Tipendra "Tapu" Jethalal Gada: Jethalal and Daya's only son, Champaklal's only grandson and Sunderlal's nephew.Vakani left the show in September 2017 and her character is shown to be living with her mother for pilgrimage. She has a catchphrase Hey Maa! Mataji! (Oh God!) whenever shocked or excited. Daya is endearingly called Garba Queen due to her passion for Garba and Annapurna (one who doesn't let anyone remain hungry) by everyone due to her excellent culinary skills. Whenever Jethalal is in the society's compound, she goes on the balcony and publicly shouts embarrassing things to Jethalal. Disha Vakani as Daya Jethalal Gada : Jethalal's wife, Tapu's mother, Champaklal's daughter-in-law and Sunderlal's elder sister.Actors like Rajpal Yadav, Ali Asgar, Kiku Sharda, Ahsaan Qureshi and Yogesh Tripathi were also considered for this role but they all rejected the role. Jethalal is Tapu's father, Champaklal's only son, Daya's husband. He's fed up by Bhide's constant blame on his son Tapu for any mischief in society.
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He is married to Daya and loves her immensely, but has a crush on his neighbour Babita Iyer. He runs a store called "Gada Electronics". Dilip Joshi as Jethalal "Jethiya" Champaklal Gada: A Kutchi Gujarati Jain from Bhachau, Gujarat.The responsibility of organising these events is often on Tapu Sena's shoulders while Bhide is tensed about exceeding the budget. The members of Gokuldham celebrate all the festivals like a family and organise various events. They help each other in their problems, to promote unity in diversity. Most of the episodes are based on Jethalal being stuck in a problem and Taarak Mehta, his best friend, whom he calls his "Fire Brigade", rescues him.
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The show also occasionally highlights social issues.
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The residents of Gokuldham are shown facing mundane problems and finding solutions for those problems. Gokuldham is also referred as "Mini India" in the show.